Standardized study of integrated traditional Chinese and western medicine on the treatment of senile hypertension

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2010
INTERVENTION: 1:the control group are given extended release nifedipine tablets 10mg bid and Enalapril Maleate Tablets 10mg bid.and if the participent couln't resist the adverse reaction,change to indapamide tablet 2.5mg qd.;2:on the basic medication of the control group ,the treatment group are given different herbal medicine according to the syndrome differentiation; CONDITION: senile hypertension PRIMARY OUTCOME: ambulatory blood pressure; SECONDARY OUTCOME: life quality, TCM syndrome scores;cystatin C, renal damage indixes; INCLUSION CRITERIA: 1. Meeting the diagnostic criteria of first and second degree of hypertension in western medicine, as well as the standard of syndrome differentiation in TCM, including the syndrome of collateral stagnation of phlegm and blood stasis, yin deficiency and yang flaming up, kidney deficiency; 2. Patients, who are newly diagnosed hypertension or doesn't administrate antihypertensive drugs more than 2 weeks, are included if their systolic blood pressure in the range of 140mmhg to 180mmhg, or their diastolic blood pressure within 90mmhg to 110mmHg after repeated measured 3 times in a week or not the same day; 3. Patients who have already administrated antihypertensive drugs with dosage and species stablely more than 2 weeks, are still included if their blood pressure are the same as above; 4. Urine level of microalbumiuria in the range of 30mg/l to 300mg/l.or the level of beta 2‐microglubulin is above 0.3mg/l; 5. Aging between 60 to 79 years old; 6. Kno
Epistemonikos ID: 4a8d62b4e4d8f58fc45cfc68f6e82c30a6d0e45a
First added on: Aug 22, 2024