No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
DISCLOSE trial is a randomized controlled trial including 532 participants with low-energy distal radius fractures. The primary objective is to evaluate whether casting without prior closed reduction is equivalent to casting following closed reduction with respect to wrist-related pain and disability, as measured by the Patient-Rated Wrist Evaluation (PRWE) score at 12 months, in patients aged 65 years or older with a displaced distal radius fracture. * Primary endpoint will be PRWE at 12 months * Follow-up visits are scheduled at 3 and 12 months. 5-year follow-up will be considered as an exploratory endpoint
Epistemonikos ID: 4a48052f4d4a3a5b8ad66759acbde602b596e8e5
First added on: Jun 28, 2025