Research on the Treatment and Molecular Mechanisms of Brain and Spinal Cord Disorders

INTERVENTION: Contrlo group:Receive standard SCS treatment with fixed stimulation parameters of frequency 40Hz, intensity 200µA, and pulse width 200µs, five times per week, 30 mi;Experimental group:Receive dynamic SCS treatment based on multidimensional assessments (pain, motor function, quality of life) and an AI prediction model. Stimulation pa;Retrospective section:None; CONDITION: Traumatic SCI with disease duration = 6 months; ASIA grade B–D PRIMARY OUTCOME: Effective rate of pain relief;Motor function improvement rate; SECONDARY OUTCOME: Pain intensity;Quality of Life;Neuroimaging indicators;Neurophysiological indicators;Motor function;Safety measures; INCLUSION CRITERIA: 1.Inclusion criteria for the experimental study: aged 18–65 years; traumatic spinal cord injury (SCI) with a disease course of <=6 months; ASIA Impairment Scale grade B–D; and provision of signed informed consent. 2.Inclusion criteria for the retrospective study: age >=18 years; diagnosed with traumatic or non‐traumatic spinal cord injury (SCI); have received spinal cord stimulation (SCS) therapy and completed at least 6 months of follow‐up; and have complete medical records, including preoperative evaluation, surgical records, stimulation parameters, and follow‐up documentation.