Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study

Peri‐implantitis is an inflammatory disease that leads to loss of jawbone around dental implants. Recent discoveries have identified increased release of Titanium (Ti) particles around implants as being associated to peri‐implantitis. In this ancillary study to the Dental Hygiene and Peri‐Implant Tissues Homeostasis trial the objective is to determine potential triggers of increased Ti dissolution from the implant surface and the mechanisms by which Ti dissolution products amplify peri‐implant inflammation. Results from this study will determine whether there is a differential response to Ti particles across individuals, which may alter susceptibility to peri‐implantitis.