NICU Utilization of Remote Voice Technology to Improve mateRnal Experience (NURTURE)

Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The study\'s objective is to conduct a Phase II randomized controlled trial examining the preliminary efficacy of the VoiceLove app compared to usual care on maternal postpartum depression in mothers with infants admitted to the Neonatal Intensive Care Unit (NICU). Primary aim: Assess the effects of VoiceLove on maternal postpartum depression, measured by the Edinburgh Postnatal Depression Scale (EPDS). As a signal-finding study, we will evaluate effect size and confidence intervals to determine whether the intervention shows promise for a future definitive Phase III trial. Secondary aim: Assess feasibility, acceptability, and patterns of communication and engagement among mothers, partners, and NICU clinicians during the NICU hospitalization, measured through app usage metrics, satisfaction surveys, and qualitative interviews. Additionally, we will evaluate effects of infant length of stay.
Epistemonikos ID: 47acf6a44cd4ad1419127246f5f1b50e9bb4120b
First added on: Oct 10, 2025