Analysis of efficacy and safety of clozapine combined with MECT treatment on refractory schizophrenia

OBJECTIVE: Learn without electricity shock (MECT) the efficacy of the treatment of schizophrenia and seizures security METHODS: 60 patients with schizophrenia were randomly divided into two groups of 30 patients in each treatment group and clozapine combined with electric shock, the control group. single with clozapine groups continued for 8 weeks, respectively, before treatment and 10 modified electric convulsive therapy using BPRS scale after the assessment of efficacy results: The treatment group was 60% efficiency, efficiency of 80%; the control group. effective rate of 40%, a significant difference before and after each treatment 66.7% efficiency (P <0.01), two groups before treatment had no significant difference (P> 0.05), there was a significant difference (P <0.01) CONCLUSION: after treatment.: clozapine combined with electric-shock therapy is superior to clozapine therapy alone rapid onset, safety, is one of the available clinical methods.