A Randomised Controlled Trial of Bolus Versus Fifteen Minute Infusion of Metoclopramide to Determine the Incidence and Severity of Drug Induced Akathisia.

INTERVENTION: A. Normal saline 10ml bolus over two minutes is placebo and then Metoclopramide Intravenous Infusion (MII): Metoclopramide 20mg in 100ml of Normal Saline as intravenous infusion over 15 minutes, is intervention. B. Metoclopramide Intravenous Bolus (MIB): Metoclopramide 20mg as 10ml bolus over 2 minutes intravenously, is the control treatment, and an infusion of Normal Saline over 15 minutes, is placebo. CONDITION: Acute drug induced akathisia (DIA) in adult Emergency Department (ED). PRIMARY OUTCOME: The rate of drug induced akathisia (DIA) as measured by a patient derived global outcome measure and the Prince Henry Hospital Akathisia Rating Scale (PHARS). SECONDARY OUTCOME: The degree of distress resulting from DIA as measured by a patient derived global score. The severity of DIA as measured by a patient derived global outcome measure and PHARS. INCLUSION CRITERIA: Patients receiving metoclopramide in the ED for any indication.