Tranexamic acid for reducing blood loss following vaginal delivery

Authors
Category Primary study
Registry of TrialsPan African Clinical Trials Registry
Year 2020
INTERVENTION: Sterile water Tranexamic acid administered to the consenting patients who meet the inclusion criteria CONDITION: ; Primary postpartum Haemorrhage Primary postpartum Haemorrhage PRIMARY OUTCOME: 1. Estimated blood loss following vaginal delivery (total blood loss following vaginal delivery= estimated blood from cylinder+ difference in the weight of pad) SECONDARY OUTCOME: 1. Primary PPH following vaginal delivery defined as blood loss > 500ml ; 2. The need for additional uterotonics to control bleeding ; 3. The need for blood transfusion (volume and amount) after vaginal delivery ; 4. Mild maternal side effects (nausea, vomiting, headache, skin rash) ; 5. Major maternal side effects (thromboembolism, maternal death) ; INCLUSION CRITERIA: 1. Spontaneous labour in booked patients 2. Planned vaginal delivery 3. Term?pregnancy 4. Singleton pregnancy and cephalic presentation 5. Parturient who has no contraindication to the use of tranexamic acid 6. Informed consent form signed
Epistemonikos ID: 471e431edd6af017810572e33cdea446e894e686
First added on: Aug 24, 2024