A Clinical trial to study the efficacy of pH based Integrated SARS Cov-2 Immunity in Human Subjects

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2020
INTERVENTION: Intervention1: 1)Clathrin Inhibition and lethal mutagenesis of virus 2)Cholecalciferol 3)Azadirachta indica Bark extract concoction 4)Arsenicum album 5)theoxanthine, theobromine, theaflavins and polyphones in tea 6)High pH diet.: After Randomisation ,study group will receive post‐exposure‐prophylaxis (PoEP ) in the form of interventions by protective factors which raise intracellular pH, for a period of 10 days,tested for blood and urinary pH ,and subsequently tested for Covid‐19 by RT‐PCR. Doses 1.Chlorpromazine‐10 mg Frequency ‐12 hourly Duration‐10 days Repeat after ‐5 weeeks. 2.NBE extract concoction Dose 10 ml Frequency‐12 hourly Duration‐10 days 3.Arsenic album 30 Dose‐5 drops daily Duration 3 days Repeat after 7 days Duration‐5 weeks 4.sunlight exposure 2 hours daily Duration‐5 weeks 5.Tea(Theoxanthine ) Dose ‐ 50 ml Frequency‐6 hourly Duration ‐5 weeks 6.High pH diet. Control Intervention1: Monitoring of health parameters and the standard treatment protocol as per ICMR guidelines.: After randomisation,those who will be in control group will be monitored for vital health parameters ,will be treated as per guidelines of ICMR for high risk Covid‐19 suspects and subsequently be tested for blood and urinary pH and Covid‐19 RT‐PCR. CONDITION: PRIMARY OUTCOME: Full(100%) protection from Covid‐19 infection and Disease.Timepoint: 5 weeks SECONDARY OUTCOME: All cause hospitalisation or mortality.Timepoint: 5 weeks INCLUSION CRITERIA: 1)High risk healthy contacts of proven Covid‐19 patients,2)suspect case of covid‐19 for whom testing for Covid‐19 could not be performed for any reason or inconclusive,3)cases with Flu like illness residing in a location reporting community transmission of Covid‐19 4) cases of Interstitial pneumonia with history of close contact of Covid‐19 patient and are covid‐19 negative by RT‐PCR 5) Healthcare workers in direct care of Covid‐19 patients. All above presenting within 5 days of exposure
Epistemonikos ID: 470afeb5a1bf5f72c63d6a766a7c2161de80c3a0
First added on: Jul 07, 2020