Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOS

This study is designed as a prospective, multicenter, parallel‐group randomizedcontrolled trial to evaluate the effectiveness of a "precision acupuncture + personalizedlifestyle" intervention, guided by dynamic multimodal risk monitoring based on the fourdiagnostic methods of Traditional Chinese Medicine (TCM), in improving insulin resistancein patients with polycystic ovary syndrome (PCOS). Compared with "conventionalacupuncture + standard lifestyle intervention," the study will primarily assess changesin the homeostatic model assessment of insulin resistance (HOMA‐IR) after 12 weeks oftreatment. The safety of the intervention, improvements in endocrine and metabolicprofiles, menstrual and ovulatory outcomes, psychological status, quality of life, andhealth‐economic outcomes will also be evaluated. The study aims to provide evidence forestablishing an intelligent and individualized clinical management model for PCOS.