Study of the effect of vitamin C in patients with Covid-19

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2020
INTERVENTION: Intervention 1: Control group: Standard Protocol Drugs (Hydroxychloroquine Sulfate Tablet 200mg Two Single Dose Pills or Chloroquine Phosphate 150mg Pill Two Single Dose Pills, Coltra Pills (Lupinavir / Ritonavir)(50/ 200)+A placebo (in terms of appearance and color similar to vitamin C) every 12 hours. Intervention 2: Intervention group: Standard Protocol Drugs (Hydroxychloroquine Sulfate Tablet 200mg Two Single Dose Pills (Tehran Drug) or Chloroquine Phosphate 150mg Pill Two Single Dose Pills (Pars), Coltra Pills (Lupinavir / Ritonavir)) 200) + Vitamin C 500mg every 12 hours for 5 days. CONDITION: Covid‐19. ; Covid‐19 U07.1 PRIMARY OUTCOME: Number of hospital days. Timepoint: Daily since hospitalization time. Method of measurement: Based on patient's file. SECONDARY OUTCOME: Blood pressure. Timepoint: Before the start of the intervention ‐ after the end of the intervention 5 days. Method of measurement: It is measured using an Sphygmomanometer. Chills. Timepoint: Before the start of the intervention ‐ after the end of the intervention, the end of 5 days. Method of measurement: Clinical observation and examination. Cough. Timepoint: Before the start of the intervention ‐ after the end of the intervention, the end of 5 days. Method of measurement: Clinical observation and examination. Fever. Timepoint: Before the start of the intervention ‐ after the end of the intervention, the end of 5 days. Method of measurement: Using oral thermometer. Level of consciousness. Timepoint: Before the start of the intervention ‐ after the end of the intervention, the end of 5 days. Method of measurement: Using the Glasgow Coma scale. Number of breaths. Timepoint: Before the start of the intervention ‐ after the end of the intervention, the end of 5 days. Method of measurement: Calculate the number of breaths per minute. Number of deaths. Timepoint: 5 days after the end of the intervention. Method of measurement: census report. Oxygen saturation of arterial blood. Timepoint: Before the start of the intervention ‐ after the end of the intervention 5 days. Method of measurement: Arterial blood pressure is measured using an pulse oximeter . INCLUSION CRITERIA: Patients who are diagnosed as Covid‐19 patients by positive PCR test or by CT Scan
Epistemonikos ID: 45572553a4a193200ee3153815e6de499f706079
First added on: Apr 23, 2020