Paravertebral Block for Improvement of Quality of Recovery Following Cardiac Surgery

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2023
This study aims to evaluate the efficacy of bilateral, paravertebral blockade (intervention) against sham blocks (control) placed prior to sternotomy in improving quality of recovery following cardiac surgery. Primary outcome: The hypothesis is that bilateral single-shot PVB at the thoracic spinal segmental levels T3/4, compared with sham blocks, improve the Quality of Recovery-15 (QoR-15) score at 24 hours following cardiac surgery by a minimally clinically important difference of 8.0 or greater. Secondary outcomes: The hypothesis is that the intervention will reduce pain scores, opioid requirements, and related side effects; improve respiratory mechanics; and facilitate a better first night\'s rest/sleep in the first 24-48 hours compared to sham blocks.
Epistemonikos ID: 45463057758fc21801b2906f37701fc5518f98da
First added on: May 15, 2024