A randomised comparison of single agent carboplatin with radiotherapy for stage I seminoma of the testis following orchidectomy

Category Primary study
Registry of TrialsISRCTN registry
Year 2000
1. To determine whether relapse rates are equivalent in patients with Stage 1 seminoma testis treated with either adjuvant radiotherapy or with single agent carboplatin at a dose of AUC 7 [7 x (GFR + 25)]. 2. To document symptoms and aspects of quality of life before and after treatment, and to compare the acute and intermediate (1-2 year) side-effects of treatment using a diary card and EORTC QLQ-C30 together with a developmental testicular tumour questionnaire. 3. To collect data on the incidence of late side-effects of treatment (such as bowel dysfunction) and second malignancies (the latter in parallel with an ongoing retrospective study of 2nd malignancies in such patients)
Epistemonikos ID: 43f9036ea8be13a5866aa3529b85d71104b5e2d1
First added on: Oct 03, 2017