Effect of Preoprative Nebulized Dexmedetomidine Compared to Nebulized Lidocaine in Attenuating Sore Throat Following Tonsillectomy In Childern

Tonsillectomy is one of the most commonly performed day‐case surgeries in pediatricpatients. Despite its routine nature, post operative sore throat (POST) remainssignificant cause of morbidity, leading to discomfort and reduced parentalsatisfaction(1) POST ranked sixth among the 10 most undesirable adverse effects relatedto general anesthesia (2). Irritation and inflammation of the airway caused by pressureexerted on the tracheal wall by the endotracheal tube (ETT)(3) trauma during intubationand mucosal dehydration(4) are thought to be the mechanistic basis for a postoperativesore throat (POST) During tonsillectomy, the shared surgical and anesthetic field poses arisk of airway manipulation, necessitating close cooperation between surgeon andanesthesiologist to maintain adequate oxygenation and a clear operative field(5)Intraoperative blood or fluid aspiration can further exacerbate upper airway irritation,contributing to POST(6) Given the impact of POST on patient well‐being, effectivepreventive strategies are essential for optimizing postoperative recovery (7)Nebulization therapy is widely used to prevent POST. It is highly recommended because ofsmall volume of drugs required for effect, easy way of administration, better patientcompliance, and most importantly little risk of adverse events compared with othermethods(such as gargle, intravenous, etc.)(8) Commonly used aerosolized drugs includecorticosteroids, ketamine, magnesium, lidocaine, Non‐steroidal anti‐inflammatorydrugs(NSAIDs), etc. and have achieved various effects(9_12) Previous studies showedpromising results for both Nebulized Dexmedetomidine and Nebulized Lidocaine inAttenuating Sore Throat(13_14) , yet no study has directly compared the efficacy ofNebulized Dexmedetomidine Versus Nebulized Lidocaine in Attenuating Sore Throat FollowingTonsillectomy.