The efficacy of combination therapy of cilostazol and acetaminophen

INTERVENTION: monotherapy Group : Cilostazol 200 mg/day Combination group : Cilostazol 200 mg/day BID + acetaminophen 800mg/day BID for the first 7 days ,followed by Cilostazol 200 mg/day BID + acetaminophen 400mg/dayBID for two weeks, and then, use of acetaminophen as‐needed at the time of onset of headache for three months. CONDITION: Ischemic stroke PRIMARY OUTCOME: frequency of headache SECONDARY OUTCOME: Withdrawal of cilostazol due to adverse effect ; Cardiovascular events; Pulse rate INCLUSION CRITERIA: 1)inpatients with ischemic stroke detected by X‐ray CT scan or MRI (non‐cardioembolic) 2)both new‐onset or recurrent ischemic stroke are permitted