AYUSH-Ayurveda guidelines: A conceptual review on the rationale in prophylaxisduring COVID -19 pandemic.

Background: COVI9 -19 is a global pandemic tightening its grip across the globe. Different systems of medicine are doing rigorous works in finding out ways to combat the SARS-CoV-2. Researches and previous pandemics have demonstrated the potential of Traditional systems like Ayurveda in managing viral infections. Aim: To explore the scientific rationale behind the AYUSH-Ayurveda guidelines and its possible in prophylaxis or Management or post-infection rehabilitation against COVID 19. Materials and Methods: Ayurveda classics were searched for relatable pathogenesis, treatment, preventive and dietary advice. An electronic search was done in PubMed/Medline, Google Scholar, and PMC using specific keywords related to AYUSH guidelines, and the data were evaluated. Result: The data from Ayurveda classics and studies from electronic databases evidenced the possible potential of the AYUSH –Ayurveda guideline in the management strategy of COVID-19. The results suggest that the guidelines take cares of multiple domains like – providing the first line of defense at the portal of entry (nasal oil installation, oil pulling, and steam inhalation); Measures to prevent mental stressors through Yoga, Pranayama, and meditation practice; Measures to maintain GUT-LUNG Axis homeostasis (Drinking Hot water & Spice usage in food and beverages) and immune modulation through Rasayana (rejuvenators) like Chyavanprasha. All the guidelines focus on improving the immune response of the host which is necessary during pandemic times. Conclusion: The current review establishes the four domains of probable action of AYUSH Ayurveda guidelines. The cost-effective, simple and time tested practices may be a possible way of integration along with the present social distancing norms and existing Government strategies in the fight against COVID -19. The potential of Ayurveda can also play a pivotal role in flattening the curve by modulation of the host immune system.