Comparing a Unani Herbal Preparation and Hydroquinone in People with Melasma

The requested reference [d7734fee29df6f3541b26b64a1a14573ad5d827c] no longer exists in our database. It has been replaced by the current reference: [94704445c78c2e1b29be621f129f4ef04afd9735]

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Topical Unani Formulation: participants will be advised to apply Topical Unani Formulation as study intervention topically on affected sites twice daily Morning and Night for 4 weeks Control Intervention1: Topical Hydroquinone: Apply once at night daily on affected site CONDITION: Health Condition 1: L818‐ Other specified disorders of pigmentation PRIMARY OUTCOME: Change in mMASI Score from baseline after 4 weeks of treatmentTimepoint: 1st 2nd 3rd and 4th weeks of study SECONDARY OUTCOME: Change in Melasma Quality of Life MELASQoL Scale Score from baseline and after 4 weeks of treatment ; Assessment of Safety Local & SystemicTimepoint: 1st 2nd 3rd and 4th weeks of study INCLUSION CRITERIA: The following participants will be included in the study Participants of any gender in the age group of 18 to 60 years diagnosed cases of Kalaf Melasma characterized by single or multiple symmetrical or asymmetrical light brown to dark brown macules and or patches distributed over the forehead malar regions nose upper lip and chin Chronicity of disease should be more than 4 months Participants who are willing to participate and comply with the protocol and to sign ICF
Epistemonikos ID: 4129c0c60b71ac96cca6549f36e01345f0d65b93
First added on: Oct 08, 2026