Improving ImmunoSuppression Adherence After Liver or Kidney Transplantation

Indication: liver (LT) or kidney Transplantation (KT) Objectives: to measure medication adherence in liver or kidney transplant patients with and without multilevel intervention programme over time Trial Design: prospective, single-centre, randomized controlled study Population: patients (male/female/diverse) between 18 and 90 years of age scheduled for LT or KT Sample Size: 75 control patients (standard of care) 75 patients in treatment group (participation in multilevel intervention programme) Statistical Analysis: The data will be analysed descriptively; continuous variables will be summarized using mean ± SD (standard deviation) or median, minimum and maximum and categorical data will be summarized using absolute and relative frequencies. For the primary outcome (Adherence to the immunosuppressive regime measured by BAASIS) and further categorical variables, differences between the groups will be assessed by the Pearson Chi-square test or Fisher\'s exact test. Group differences for continuous parameters will be assessed by the two-sample T-test or Mann-Whitney-U-test as appropriate. Trial Duration and Dates: November 2019-October 2021