The effect of epigallocatechin gallate (extracted from green tea) loaded nanostructured lipid carriers on the treatment of oral lichen planus

INTERVENTION: Intervention 1: Intervention group: Mouthwash containing Epigallocatechin gallate loaded nanostructured lipid carriers will be used 3 times a day, 5 cc each time for 4 weeks. Intervention 2: Control group: Mouthwash containing Epigallocatechin gallate will be used 3 times a day, 5 cc each time for 4 weeks. CONDITION: L43.8 oral lichen planus. ; Other lichen planus PRIMARY OUTCOME: Severity of pain. Timepoint: Before the start of the intervention and 2 and 4 weeks after the intervention. Method of measurement: The severity of pain will be evaluated through visual analogue scale (VAS). The appearance of lesions. Timepoint: Before the start of the intervention and 2 and 4 weeks after the intervention. Method of measurement: The appearance of lesions will be measured by Thongprasom scale and includes 6 grades: zero = perfectly healthy, 1 = mild white lines without inflammatory regions, 2 = white lines with atrophic regions smaller than 1 cm2, 3 = white lines with atrophic regions larger than 1 cm2, 4 = white lines accompanied with erosive regions less than 1 cm2, 5 = white lines with erosive areas larger than 1 cm2 . The size of lesions. Timepoint: Before the start of the intervention and 2 and 4 weeks after the intervention. Method of measurement: The size of lesions will be measured with paper lace. INCLUSION CRITERIA: Definite Diagnosis of Lichen Planus via Clinial criteria and Histopathology approvement Range of 17 to 70 years old