The efficacy of playing the Ninntendo DS games on cognitive functions of healthy elderly: a randomaized controlled trial

INTERVENTION: Playing a brain training game once a day, and 15 minutes for 4 weeks Playing a puzzle game once a day, and 15 minutes for 4 weeks CONDITION: Healthy elderly PRIMARY OUTCOME: 1)Mini‐Mental State Examination (MMSE) ; 2)Frontal assessment battery at bedside (FAB); 3)Trail Making Test‐B (TMT‐B); 4)Digit cancellation task (D‐CAT; 5)digit span forward (DS‐F); 6)digit span backward (DS‐B); 7)Digit Symbol Coding (Cd); 8)Symbol Search (SS) SECONDARY OUTCOME: 1)Brain structure measured by MRI INCLUSION CRITERIA: 1.Age:65‐75 2.Right‐handed person