Study of Mahapaisachika Ghrita Compared with Escitalopram for Mild to Moderate Depression in Older Adults

INTERVENTION: CONDITION: Health Condition 1: F320‐ Major depressive disorder, singleepisode, mild Health Condition 2: F321‐ Major depressive disorder, singleepisode, moderate PRIMARY OUTCOME: Mean change in Hamilton Depression Rating Scale total score from baseline Day 0 to Day 45.Timepoint: Day 45 SECONDARY OUTCOME: Mean change in individual HAM D 17 symptom domain scores from baseline Day 0 to Day 45Timepoint: Day 45 Mean change in WHOQOL‐BREF domain scores from baseline Day 0 to Day 45.Timepoint: Day 45 INCLUSION CRITERIA: Age 60 years and above at the time of enrolment, irrespective of gender. Diagnosis of mild to moderate depressive episode according to ICD 11 criteria, established through structured psychiatric assessment. Hamilton Depression Rating Scale 17 item total score between 8 and 23 at baseline.