Effects of an alpha2 adrenergic agonist and a beta adrenergic antagonist on disturbance of visual function in glaucoma

INTERVENTION: Intervention name : brimonidine tartrate Dosage And administration of the intervention : Ocular administration Control intervention name : timolol maleate Dosage And administration of the control intervention : Ocular administration CONDITION: Primary open‐angle glaucoma (POAG) PRIMARY OUTCOME: retinal sensitivity SECONDARY OUTCOME: intraocular pressure(IOP); Optical coherence tomographic(OCT) finding; retinal perfusion INCLUSION CRITERIA: Patients had POAG Mean deviation>=‐20dB IOP<=21.0mmHg Best corrected visual acuity of 0.5 or better