Bioactives-Enhanced Sunscreen Trial (BEST): Evaluating the effect of a Mineral Sunscreen containing Bioactive agents against Standard Sunscreen use on Sun Damage and Pre-cancerous lesions

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2021
INTERVENTION: Daily use of a mineral sunscreen containing bioactive agents (even when no sun exposure planned); intra‐patient on one side the bioactive sunscreen daily (ipsilateral limb, and on the other (contralateral limb) standard moisturiser and (participant s previous) sunscreen use episodically as participant has been doing over the years. The anatomical side of each limb will be randomised. ‐ mode of administration: sunscreen application on sites as directed on the container. ‐ the duration and frequency of administration: once daily for the duration of the trial. Expected 3‐9 months (including follow up period). ‐ strategies used to monitor adherence to the intervention: sunscreen diary to be reviewed during follow up visits ‐ depending on the review visit assessment, the sunscreen use may be continued longer and data collected. CONDITION: actinic keratosis;sundamage from UV and other radiation; ; actinic keratosis ; sundamage from UV and other radiation Public Health ‐ Health promotion/education Skin ‐ Dermatological conditions PRIMARY OUTCOME: Change in number actinic keratoses ‐ monitored by clinical counts (by physician)[3 months post‐intervention commencement] SECONDARY OUTCOME: Change in sun damage of skin‐ monitored by examination with lamps such as Wood's lamp or other similar scans[3 months] INCLUSION CRITERIA: People with outdoor exposure lifestyles, and fair skin (Fitzpatrick I and II) with higher risk of skin cancer) that are regular uses of sunscreen
Epistemonikos ID: 3e3abb55eb159389fcd38b10f7a5f27d564c8bdf
First added on: Aug 25, 2024