No-tox Vs. Retinoid (Tretinoin) Study: Comparison of the wrinkle reduction performance of a cosmeceutical non-toxin based wrinkle-reducing serum against a pharmaceutical prescription-grade retinol

INTERVENTION: No‐Tox serum (manufactured under license by Smoothe Inc, DE, USA) will be applied twice daily over wrinkled areas of the face (4‐5 drops twice daily as recommended by the manufacturers). The cosmetic formulation contains plukenitia volubis, niacinamide, hyaluronic acid and plankton extracts (detailed ingredient list under documents) Measurements and clinical reviews will be undertaken at 1‐month and 3‐month periods on healthy adult volunteers. The amount of product provided has been estimated to last 3 months at which the empty containers will be returned. CONDITION: Skin ‐ Other skin conditions Wrinkling due to skin damage caused by exposure to sunlight; ; Wrinkling due to skin damage caused by exposure to sunlight PRIMARY OUTCOME: Any change in wrinkle count or depth (measured using fluorescence spectroscopic facial scanner)[1 month and 3 months after study commencement] SECONDARY OUTCOME: Any skin sensitivity or skin irritation that occurs in either arm of the study will be evaluated using participant questionnaires designed specifically for the study..[From Day 1 of treatment until conclusion of the study.] INCLUSION CRITERIA: Healthy volunteers, aged between 25 and 75 without acute or chronic skin diseases will be enrolled.