Variable presentation of acute posterior multifocal placoid pigment epitheliopathy in Pakistan

Seven acute posterior multifocal placoid pigment epitheliopathy [APMPPE] patients from Pakistan had widely variable presentation and outcome. These patients, ranging in age from 16 to 50, were seen during the period from March 1990 to September 1991 at the Department of Ophthalmology, Dow Medical College, Karachi. Four cases were bilateral and three unilateral. Only one patient presented with associatd headache and systemic symptoms, but other six gave a history of preceding flu-like illness. Outcome varied from near full recovery to a marked reducation in vision with persistent paracentral scotomas. One 24-year-old woman also had bilateral deep macular hemorrhage. [Pakistan Journal of Ophthalmology 8:61-66, July, 1992]