Comparative efficacy of Nigella sativa (black sseds)5% v/v gel and triamcinolone 0.1% in oral lichen planus-A Pilot Study

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Nigella sativa gel 5% v/v (Black seed gel): 15 patients with clinically diagnosed cases of symptomatic Oral Lichen Planus who will be given medicinal management of Nigella sativa gel. Control Intervention1: Triamcinolone Acetonide Buccal Paste 0.1 % w/w (Caziq): 15 patients with clinically diagnosed cases of symptomatic Oral Lichen Planus who will be given medicinal management of topical Triamcinolone Acetonide paste. CONDITION: Health Condition 1: L089‐ Local infection of the skin and subcutaneous tissue, unspecified PRIMARY OUTCOME: This study will be carried to assess the effectiveness of N. sativa in comparison with triamcinolone acetonide, in reducing pain and burning sensation, as well as their effects on improvement of oral lesions.Timepoint: This study will be carried to assess the effectiveness of N. sativa in comparison with triamcinolone acetonide, in reducing pain and burning sensation, as well as their effects on improvement of oral lesions. SECONDARY OUTCOME: This study will be carried to assess the effectiveness of N. sativa in comparison with triamcinolone acetonide, in reducing pain and burning sensation, as well as their effects on improvement of oral lesions.Timepoint: INCLUSION CRITERIA: 1. Patients aged between 18 to 55 years of age of either gender. 2. Patients with clinically diagnosed cases of symptomatic reticular/erosive oral lichen planus. 3. Patients with OLP who have not received any treatment for the lesions in the past 4 weeks will be included. 4. Patient voluntarily willing to be a part of the study after signing the informed consent
Epistemonikos ID: 3c4a04f70f2f6ce23b270c0df771db2df426b410
First added on: Jul 25, 2026