Cognicise Training for Seniors for Healthy Aging

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The goal of this clinical trial is to assess the impact of two 8-week motor-cognitive exercise programs - Cognicise and yoga - on psychological, respiratory, cardiovascular, postural, and biochemical health in elderly women. The main objectives are to evaluate whether these programs: Improve psychological parameters such as mood, quality of life, depressive symptoms, and cognitive abilities; Enhance respiratory function, including lung volumes and ventilation; Influence cardiovascular parameters such as blood pressure and heart rate; Improve chest mobility, physical fitness, and cardiorespiratory capacity; Induce favorable changes in selected blood biomarkers, including neurotrophic factors, hormones, glucose, lipids, and blood morphology; Improve postural stability, as assessed through posturographic analysis. The study compares the effects of yoga and Cognicise to a control group that does not receive any intervention. Participants in the yoga and Cognicise groups will take part in supervised sessions twice a week for 8 weeks (each session lasting 45 minutes). Participants from all three groups (yoga, Cognicise, and control) will undergo pre- and post-intervention assessments, including: Psychological questionnaires; Spirometry and cardiorespiratory tests; Blood pressure and heart rate measurements; Chest mobility and physical fitness tests; Posturographic assessment of postural control during quiet standing with eyes open and closed; Laboratory blood tests (including BDNF, GDNF, 25(OH)D, TSH, testosterone, cortisol, insulin, glucose, lipid profile, and complete blood count with differential). The aim is to determine whether structured motor-cognitive training leads to measurable health benefits compared to no intervention.
Epistemonikos ID: 3bf6a2b17e80ac4af2b73da9219ac096f54514d1
First added on: Aug 02, 2025