Comparison of the effect of Carvacrol gel, and Chlorhexidine in reducing postoperative pain, and dry socket after surgical removal of impacted mandibular third molars- a clinical trial

INTERVENTION: Intervention 1: Control group: do not receive any kind of mouthwash. Intervention 2: Intervention group I: Rinse once with 0.2%chlorhexidine mouthwash pre‐operatively. Intervention 3: Intervention group II: in which 0.5 % w/w Carvacrol‐based gel is placed in the socket after the surgery. Intervention 4: Intervention group III: vehicle gel treated group. CONDITION: Condition 1: Pain. Condition 2: Dry socket. Condition 3: Total analgesic drug consumption. ; Pain, unspecified ; Other nonsteroidal anti‐inflammatory drugs [NSAID] Y45.3 PRIMARY OUTCOME: Dry socket. Timepoint: Seventh day post‐operation. Method of measurement: Intraoral examination for signs of dry socket. Pain. Timepoint: The first, second and seventh days after surgery. Method of measurement: Visual analog scale (asking from patient, scoring from 1 to 10). SECONDARY OUTCOME: Number of pain relief tablets taken. Timepoint: The first, second and seventh days after surgery. Method of measurement: Asking the patient. INCLUSION CRITERIA: All adult patients (over 18 years old) healthy without any systemic disease Absent history of dry socket Having one or two impacted wisdom teeth (surgery on one side only) The presence of adjacent second molars No antibiotics and anti‐inflammatory intake at least 7 days before surgery)