Clinical trial of the effect of curcumin on treatment of oral lichen planus

INTERVENTION: Intervention 1: Control group: Receives corticosteroid mouthwash (triamcinolone acetone 40mg in 1 ml with 19 cc distilled water, 5 cc each time) 3 times daily with antifungal mouthwash (20 drops of 100,000 IU oral suspension nystatin, 3 times/day) in addition to placebo capsules, once a day, after breakfast, for 4 weeks. Intervention 2: Intervention group: In the intervention group, in addition to the standard treatment similar to the control group, curcumin capsules manufactured by Sina Co. with brand name of "Sina curcumin" containing 80 mg nanocrystalline curcumin are used once a day after breakfast for 4 weeks. In both groups, the patient uses the mouthwash for 2 minutes and then spits out and avoids eating and drinking for up to 30 minutes thereafter. CONDITION: Oral Lichen Planus. ; Lichen plaus PRIMARY OUTCOME: Pain and Soreness. Timepoint: Before treatment and 2 , 4 weeks after treatment. Method of measurement: Asking from patients, based on visual analogue scale (VAS) and between 0‐10. Scoring and appearance of oral lichen planus lesions. Timepoint: Before treatment and 2 , 4 weeks after treatment. Method of measurement: Observation. Size of the lesion. Timepoint: Before treatment and 2 , 4 weeks after treatment. Method of measurement: by the Michigan 'O' Probe in mm. INCLUSION CRITERIA: Age 30‐70 years Diagnosis of oral lichen planus with biopsy