Effect of intranasal dexmedetomidine hydrochloride on anxiety in patients undergoing laparoscopic surgery

INTERVENTION: Control group:A placebo nasal spray was used for administration, with the drug delivered through both nostrils – 2 sprays per nostril, for a total of 4 sprays (the total dose in group D was 100µg).;Dexmedetomidine group:Dexmedetomidine hydrochloride nasal spray was sprayed by the researchers through bilateral nasal cavities 60 minutes before operation in the preoperat; CONDITION: Preoperative anxiety in patients undergoing laparoscopic surgery PRIMARY OUTCOME: Hospital Anxiety and Depression Scale (HADS) score; SECONDARY OUTCOME: Ramsay Sedation Scale;Adverse reaction indicators: nausea and vomiting, respiratory depression, severe bradycardia (hr<50 times/min), hypotension,;Vital signs: heart rate (HR), mean arterial pressure (MBP), respiratory rate (RR), blood oxygen saturation (SpO2)); INCLUSION CRITERIA: 1.Age 18‐70 years; 2.ASA physical status class I‐II; 3.Scheduled for elective laparoscopic surgery under general anesthesia; 4.Able to express themselves verbally or read, and able to understand and complete the questionnaire independently or the assistance of a physician.