Topical beta-blockers for the treatment of Paronychia

INTERVENTION: Randomized CONDITION: Paronychia induced by EGFR inhibitors PRIMARY OUTCOME: Comparison between complete response and partial response of; granuloma at week 8 SECONDARY OUTCOME: Safety and adverse effects during the trial period; Improvement of periungual erythema and granuloma at week 4; Improvement of periungual erythema and granuloma at week 8 INCLUSION CRITERIA: (1) Patients over the age of 20 with Grade 2 of paronychia caused by EGFR inhibitors (2) Ambulatory patients can answer survey questions (3) Patients must receive substantial and sufficient explanation of the content of this trial in all its aspects and provide. (4) Patients with self‐management of skin and nail care