A Study in Parkinson's Disease in paTients With mOderate to seveRe dyskInesiA

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2019
This is a Phase 2, double‐blind, double‐dummy, placebo‐controlled, randomized, parallel group, multicentre study. Subjects with a diagnosis of moderate to severe dyskinesia in Parkinson's disease (PD) will complete a Screening Visit to assess eligibility to participate in the study. Subjects will continue with their usual levodopa treatment regimen for the duration of study participation. The screening assessment period will be a minimum of 1 week up to a maximum of 6 weeks. Subjects deemed to be eligible at the end of the Screening Visit will be randomly assigned in a 1:1:1 ratio to receive either 1 of the 2 dose combinations of JM‐010 and 1 placebo, or 2 placebos as per the double‐dummy study design. The randomized subjects will be followed treatment periods for 12 weeks and safety follow periods for 2 weeks, including pharmacokinetic (PK) sub‐study.
Epistemonikos ID: 3a8b8f6e43b7add5a21475393a1fab35b9c8eca0
First added on: May 22, 2024