To Evaluate and Compare the Effect of Orthograde and Retrograde MTA Root End Filling After Periapical Surgery in Posteriors

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
RATIONALE:Mineral Trioxide Aggregate (MTA) has long been established as a reliable material inretrograde filling techniques, with extensive evidence supporting its biocompatibilityand sealing ability. However, the use of MTA as orthograde root end filling has not beenexplored, leaving a gap in clinical evidence. Retrograde placement allows directvisualization whereas orthograde filling offers a less invasive approach that couldpotentially reduce patient morbidity and improve comfort. Comparing these two techniquesis essential to determine whether orthograde MTA filling can achieve comparable orsuperior healing outcomes while enhancing patient quality of life. This study aims tosystematically assess both approaches, providing evidence‐based insights that may guideclinicians toward more effective and patient‐friendly treatment strategies.Aim: To evaluate and compare the effect of orthograde and retrograde MTA root end fillingon clinical, 2D and 3D radiographic success and quality of life after periapical surgeryin posteriors‐ A Randomised Control TrialPrimary objective: To evaluate and compare the effect of orthograde root end filling andretrograde root end filling on 2D and 3D radiographic and clinical healing at 1 yearfollow upSecondary objective: To evaluate the quality of life after orthograde and retrograde rootend fillingSetting: Study will be conducted in Post Graduate Institute of Dental Sciences, Rohtak inthe department of Conservative Dentistry & Endodontics.Study design: A randomized controlled trialTime frame: 12Months
Epistemonikos ID: 39a2359b1ddc121b7d25024e0046aa03c96ad603
First added on: Sep 09, 2026