A clinical study to compare three different antimicrobial solutions to be used inside the milk teeth of children aged 4 to 8 years for infection removal and healing.

INTERVENTION: Intervention1: 10.2% Curcumin intracanal irrigant : The intervention study group is termed as G3 (Group 3) where Curcumin (10.2%) intracanal irrigant, 10 mL for 1 minute, single application during LSTR procedure (freshly prepared in distilled water). In all groups, after irrigation, Double Antibiotic Paste (metronidazole + ciprofloxacin) will be placed followed by zinc oxide eugenol restoration, glass ionomer cement, and stainless‐steel crown. Follow‐up at 1, 3, 6, and 9 months. Control Intervention1: 2.5% Sodium hypochlorite and 2% Chlorhexidine gluconate intracanal irrigants: Group 1: Sodium hypochlorite (2.5%) intracanal irrigant, 10 mL for 1 minute, single application during LSTR procedure. Group 2: Chlorhexidine gluconate (2%) intracanal irrigant, 10 mL for 1 minute, single application during LSTR procedure. CONDITION: Health Condition 1: K041‐ Necrosis of pulp PRIMARY OUTCOME: Clinical success defined by absence of pain, swelling, sinus/fistula, and tenderness on percussionTimepoint: 01 month ; 03 months ; 06 months ; 09 months SECONDARY OUTCOME: Radiographic healing (reduction in radiolucency, improvement in lamina dura, bone regeneration) ; Root resorption status (physiologic/pathologic)Timepoint: 01 month ; 03 months ; 06 months ; 09 months INCLUSION CRITERIA: Presence of any one in each category: CLINICAL CRITERIA:‐ 1. Deep carious lesion with pulp exposure 2. Signs of irreversible pulpitis or non‐vitality 3. Pulpotomy treated tooth showing signs of radicular pulpal necrosis or irreversible pulpitis. RADIOGRAPHIC CRITERIA: 1. Discontinuity of lamina dura 2. Periapical and inter‐radicular radiolucency 3. Furcation involvement