Transcranial direct current stimulation for cognitive enhancement in older adults with mental disorders: a systematic review.

OBJECTIVE: We systematically reviewed the literature regarding the use of transcranial direct current stimulation in older adults with any psychiatric disorder and cognitive impairment, focusing on its potential to enhance cognitive functions, particularly working memory. METHODS: Data extracted included stimulation parameters, patient characteristics, and cognitive outcomes. RESULTS: Findings were mixed; variations may be due to differences in stimulation parameters, disease severity, and neuroanatomy. CONCLUSION: Combining transcranial direct current stimulation with cognitive training showed synergistic effects.