Efficacy of Consuming LcS In Spinal cord injury Patients (ECLISP)

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2015
INTERVENTION: Lactobacillus casei Shirota. One bottle of Yakult containing 6.5x10/9 Lactobacillus casei Shirota once a day during the course of antibiotics and for 7 days after the course finishes. CONDITION: Antibiotic associated/Clostridium difficile diarrhoea ; Infections and Infestations PRIMARY OUTCOME: Occurrence of antibiotic‐associated dairrhoea: Timepoint(s): 30 days SECONDARY OUTCOME: Analyse the effect of LcS on:; 1. Occurrence of C. difficile diarrhoea; 2. Duration of diarrhoea; 3. Gastrointestinal microbiota; 4. Quality of life; ; Measured 30 days after finishing probiotic/placebo. INCLUSION CRITERIA: 1. Adult (=18 years) 2. Patient is likely to remain in the Spinal Cord Injury Centre (SCIC) for more than 6 weeks can be included 3. Newly started antibiotics (for a minimum of 3 days) (single or multiple)
Epistemonikos ID: 392ad8c85c975c9b8e48520ce985bd72ffc15ecc
First added on: Aug 23, 2024