Modified acellular dermal matrix repair combined with opening suture and drainage in the treatment of Uygur high complex anal fistula in Xinjiang

Background: Surgical methods for high complex anal fistula have certain recurrence rate and a series of problems such as anal dysfunction in the world. Objective: To discuss the clinical application of modified acellular dermal matrix repair combined with opening suture and drainage technique for the treatment of Uygur high complex anal fistula in Xinjiang. Methods: Forty cases of Uygur high complex anal fistula in Xinjiang were selected. All the cases were randomly divided into experimental group and control group. Cases in the experimental group were treated using modified acellular dermal matrix repair combined with opening suture and drainage technique, and the cases in the control group were treated with traditional drainage. Results and Conclusion: There was no significant difference in the aspect of fistula closure time, recover rate and postoperative pain score between two groups (P > 0.05). However, the aspect of postoperative pain time, hospitalization time and life quality scores in the experimental group were significantly better than those in the control group (P < 0.05). Modified acellular dermal matrix repair combined with opening suture and drainage has a certain effect on the healing of high complex anal fistula. However, the safety and efficacy of this method needs further multi-center and randomized controlled clinical trials to verify.