Efficacy, Immunogenicity and Safety Study of GSK Biologicals' Candidate Malaria Vaccine Evaluating Different Dose Schedules in a Sporozoite Challenge Model in Healthy Malaria-naïve Adults

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2017
This study is designed to evaluate efficacy, immunogenicity and safety of various dose schedules of GSK Biologicals\' candidate malaria vaccines RTS,S/AS01B (adult formulation) and RTS,S/AS01E (pediatric formulation) in healthy malaria-naïve subjects aged 18-55 years. The purpose of this study is to investigate whether changes in dosing schedule are associated with increased or equivalent protection, and to evaluate the immune mechanisms associated with vaccine efficacy under varying dosing schedules.
Epistemonikos ID: 38354aec80f074c931a521bf8c9ad23f60ad39fb
First added on: May 20, 2024