Anthocyanin Rich Extract (ACRE) in Patients With Ulcerative Colitis

For anthocyanins (ACs), a wide range of protective biological effects have been described, such as anti‐oxidative, anti‐carcinogenic, anti‐microbial and anti‐inflammatory activities. Various research groups could identify a beneficial effect of ACs in IBD and intestinal inflammation. A total of 112 subjects will be randomized. Subjects will be screened for eligibility between 0 and 28 days prior to baseline visit. At the baseline visit, subjects with moderate to severe ulcerative colitis (Mayo score ≥6) and fulfilling all inclusion/exclusion criteria will be randomized into two treatment arms (ACRE or placebo). Total duration of drug product administration will be 8 weeks (56 days) followed by a follow‐up phase of 30 days.