A Randomized Controlled Trial on the Efficacy of Acupoint Catgut Embedding Combined with Ursodeoxycholic Acid in Dissolving Cholesterol Gallstones and Its Impact on Gallbladder Function

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Acupoint Catgut Embedding + UDCA Group:Acupoint catgut embedding with PGLA absorbable sutures at Yanglingquan, Danshu, Riyue, and Gallbladder point, deep implantation, once every 2 weeks for 4 sessions (8‐week course); Ursodeoxycholic acid (UDCA): 10 mg/kg/day, oral nightly, for 12 weeks;Acupuncture + UDCA Group:Acupuncture at Yanglingquan, Danshu, Riyue, and Gallbladder point with superficial puncture (conventional acupuncture), once every 2 weeks for 4 sessions; Ursodeoxycholic acid (UDCA): 10 mg/kg/day, oral nightly, for 12 weeks; CONDITION: Gallbladder Cholesterol Stones PRIMARY OUTCOME: Complete stone dissolution rate; SECONDARY OUTCOME: Partial stone dissolution rate;Gallbladder function recovery;Clinical symptom relief;Quality of life improvement; INCLUSION CRITERIA: 1. Aged 18–65 years; 2. Diagnosed with gallbladder cholesterol stones by ultrasonography (diameter = 10 mm); 3. Reduced gallbladder contractile function (GBEF = 35%); 4. Patency of the cystic duct; 5. No recent acute complications; 6. Voluntary signing of informed consent.
Epistemonikos ID: 36f75e920c3f0bd45c9d91e79ae1c223f4c0084e
First added on: Jul 21, 2026