Category
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Primary study
Registry of Trials»Iranian Registry of Clinical Trials
Year
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2021
Links
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INTERVENTION: Intervention 1: Intervention group: Patients will be treated daily with topical guar gum gel containing licorice root extract for three weeks delivered from a thin layer of the contents of the drug. Intervention 2: Control group: Patients will be treated daily with Silver Sulfadiazine Ointment for three weeks delivered from a thin layer of the contents of the drug. CONDITION: Burn. ; Burn of second degree of trunk, unspecified site T21.20 PRIMARY OUTCOME: Mean time of wound healing. Timepoint: The wound healing process is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment on the wound area. Method of measurement: Clinical examination. The rate of flexibility. Timepoint: The rate of flexibility is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment in the wound area. Method of measurement: Clinical examination. The rate of pain. Timepoint: The rate of pain is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment in the wound area. Method of measurement: Clinical examination. The rate of pigmentation. Timepoint: The rate of pigmentation is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment in the wound area. Method of measurement: Clinical examination. The rate of pruritus. Timepoint: The rate of pruritus is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment in the wound area. Method of measurement: Clinical examination. The rate of thickness. Timepoint: The rate of thickness is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment in the wound area. Method of measurement: Clinical examination. The severity of vascularity. Timepoint: The severity of vascularity is measured during the study period on days 1, 3, 7, 10, 14, and 21 after starting to use Licorice gel and Silver Sulfadiazine ointment in the wound area. Method of measurement: Clinical examination. SECONDARY OUTCOME: Complications observed. Timepoint: End of the study. Method of measurement: Based on the doctor's observation and the person's statements. Life quality. Timepoint: End of the study. Method of measurement: According to "Quality of Life Questionnaire (QLQ‐C30) version 3" of European Organization for Research and Treatment of Cancer (EORTC). INCLUSION CRITERIA: Presenting to the burn center in the first 24 hours after the burn Having grade II burns, superficial and deep, that involve less than 10% of the body's surface area No comorbidity that delays the repair process (such as diabetes, chronic kidney disease, malignancy, and chronic use of corticosteroids) Absence of respiratory burns as well as chemicals or electric burn No burns on the face and perineum
Epistemonikos ID: 36ee00993e22a5507c935ddaaa0d124df9ccadd5
First added on: Aug 24, 2024