450 nm Blue Diode Laser Versus Blue LED for In-Office Tooth Bleaching

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
Tooth discoloration is commonly managed using in-office dental bleaching. This randomized clinical trial compared the efficacy and safety of activating the same 35% hydrogen peroxide bleaching gel with either a 450 nm blue diode laser or a conventional blue light-emitting diode lamp. Forty participants aged 18 to 25 years were randomly assigned in a 1:1 ratio to one of the two interventions. The primary outcome was postoperative tooth hypersensitivity immediately after treatment. Secondary outcomes included immediate tooth-color change, color stability at 4 weeks, 8 weeks, and 6 months, gingival irritation, and patient satisfaction. Participants and outcome assessors were blinded to group allocation, whereas the treating operator could not be blinded because the devices were visibly different.
Epistemonikos ID: 36df82748921f56b8ad4b9c700d174bb7dd2fe63
First added on: Oct 14, 2026