PRE-EMPT: Prevention of Mood Disorders by Folic Acid Supplement.

INTERVENTION: Trade Name: Lexpec Pharmaceutical Form: Pharmaceutical form of the placebo: Syrup Route of administration of the placebo: Oral use CONDITION: Mood disorder PRIMARY OUTCOME: Main Objective: Prevention of mood disorder in "at‐risk" individuals. Primary end point(s): Occurence of Axis I mood disorder on DSM‐IV diagnostic schedule.; ; Secondary Objective: Decrease in depressive symptoms and improved well‐being. INCLUSION CRITERIA: Teenage child of biological parent with mood disorder. Are the trial subjects under 18? yes Number of subjects for this age range: F.1.2 Adults (18‐64 years) yes F.1.2.1 Number of subjects for this age range F.1.3 Elderly (>=65 years) no F.1.3.1 Number of subjects for this age range