A study in women undergoing breast cancer surgery to evaluate whether Tab melatonin given before surgery reduces the need for pain medicine during the operation.

INTERVENTION: Intervention1: Tab Melatonin: Tab Melatonin (0.3mg/kg ) orally, Once 120 minutes before surgery. Control Intervention1: Tab Multivitamin: Tab multivitamin, orally, once 120mins before surgery. CONDITION: Health Condition 1: O‐ Medical and Surgical PRIMARY OUTCOME: To compare the total intraoperative fentanyl consumption between patients receiving melatonin as premedication and those receiving placebo.Timepoint: Total intra operative Fentanyl consumption SECONDARY OUTCOME: Hemodynamic variability in both the groups intraoperatively at 0,30,60,90,120,150,180 mins ; Timepoint: Intraoperative To assess the effect of melatonin on intubation responseTimepoint: Intraoperative To assess the first rescue analgesia. ; Timepoint: Post‐operative To determine the effect of melatonin as anxiolytic before induction by Ramsay Sedation Score and post extubationTimepoint: Intraoperative and postoperative ; Use of other additives for intraoperative pain response.Timepoint: Intraoperative INCLUSION CRITERIA: American Society of Anaesthesiologist physical status 1 or 2 Patient giving informed consent