Assessment of Microbiological Profile of Dengue Fever among Patients: An Institutional Based Study

Background: Dengue is believed to infect 50 to 100 million people worldwide in a year. Dengue is a major challenge to public health, especially in South-East Asia. The present study assessed microbiological profile of Dengue fever among patients. Methods: This study was conducted on 120 patients found serologically positive for dengue fever. Rapid immune chromatography method was used for detection of NS1 antigen, and IgM antibody. Results: Common clinical manifestation were headache (20%), vomiting (44%), headache (20%), abdominal pain (19%), myalgia (7%),hepatomegaly (42%) and bleeding (12%). The difference was significant (P<0.05). 85% found positive for NS1 and IgM (7%). 8% samples found positive for NS1 and IgM. The difference was significant (P<0.05). 13 patients developed complications of dengue shock syndrome and 7 developed dengue hemorrhagic syndrome. Conclusion: Diagnosis of dengue fever in children is challenging. Dengue fever can be diagnosed with different laboratory tests. Among all is detection of NS1 antigen which may be considered as early diagnostic marker for dengue fever.