A multicenter, randomized, double-blind, placebo-controlled post marketing clinical trial to evaluate the efficacy and safety of Dong'e Ejiao in the treatment of early-onset ovarian insufficiency (blood deficiency syndrome)

INTERVENTION: control group:Dong'e Ejiao mimetic (powder): 9g / bag, 1 bag / time, 1 time / day, boiled water;experimental group:Dong'e Ejiao (powder): 9g / bag, 1 bag / time, 1 time / day, boiled water; CONDITION: Early onset ovarian insufficiency PRIMARY OUTCOME: FSH; SECONDARY OUTCOME: AMH;Transvaginal ultrasound;Five items of se Xhormone;AMH;Kupperman;AMH; INCLUSION CRITERIA: (1) Consistent with the diagnosis of early‐onset ovarian insufficiency; (2) In accordance with the syndrome differentiation of blood deficiency; (3) At baseline, serum follicle stimulating hormone (FSH): 25‐40u / L; (4) Voluntarily participate in this clinical trial, give informed consent and sign the informed consent form.