Macrogole Versus Sodium Picosulfate in Bowel Cleansing for Colonoscopy in Pediatric Inflammatory Bowel Disease

Children hospitalized at the Department of Pediatric Gastroenterology and Nutrition atthe Medical University of Warsaw with suspected or confirmed inflammatory bowel disease(IBD) will be invited to participate in the study.Data regarding demographics, current body weight, height, and the number of daily bowelmovements during the week prior to the colonoscopy will be collected for each patient.On the day before the colonoscopy, all patients will be placed on a low‐residue dietuntil 3:00 PM. Children will be randomly assigned‐based on a computer‐generatedrandomization list‐to one of two groups: ‐ one group will receive a high‐volume polyethylene glycol (PEG)‐based preparation ata dose of 100 ml/kg of body weight (maximum 4 liters), ‐ the other group will receive a low‐volume preparation containing sodium picosulfateand magnesium oxide at the following doses: for patients ≤9 years of age, two dosesof ½ sachet (150 ml total); for patients >9 years of age, two doses of 1 sachet (300ml total); along with an appropriate volume of fluids: a minimum of 1500 ml forpatients ≤9 years of age and a minimum of 3000 ml for patients >9 years of age.The children will receive the preparations after 3:00 PM on the day before thecolonoscopy. In addition to the aforementioned fluid intake, the patient may consume anyamount of clear fluids; the total volume of fluids consumed will be recorded in thepatient's chart.Each patient will receive detailed written instructions outlining the individual dosageof the preparation and the colonoscopy preparation regimen. Additionally, a discussionwill be held with the patient and their parent or guardian to review the preparationprocess and emphasize the importance of proper bowel cleansing for the quality of theexamination.The quality of bowel preparation will be assessed using the Bristol Bowel PreparationScale (BBPS) scale by the physician performing the colonoscopy.The patient and their parent or guardian will rate the tolerability of the colonoscopypreparation using a 10‐point visual analogue scale.In all cases, a prerequisite for inclusion in the study will be obtaining written orverbal consent from the child's parents or guardians and from any child over the age of16, as well as from a younger child if they are capable of understanding the purpose ofthe study.