A Clinical Study to Assess the Efficacy of a Calcium Sodium Phosphosilicate Toothpaste for the Relief of Dentine Hypersensitivity

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This will be a single centre, 8‐week, randomised, controlled, double‐blind, 2‐treatmentarm, parallel group, stratified study in healthy participants with DH. Participants whomeet the required study criteria at Screening and Baseline will be randomised to one oftwo treatments: a 5% CSPS toothpaste (Test Toothpaste) or a regular sodium fluoridetoothpaste (Reference Toothpaste). Sufficient participants will be screened to ensureapproximately 192 participants are randomised to investigational products (approximately96 participants per treatment group) and approximately 172 participants complete thestudy (approximately 86 participants per treatment group).
Epistemonikos ID: 336e108ea24730e1c49394e6edc2323345450a4f
First added on: Sep 03, 2026