Rapid emergence of high-level resistance to quinolones in Campylobacter jejuni associated with mutational changes in gyrA and parC.

Category Primary study
JournalAntimicrobial agents and chemotherapy
Year 1998
Quinolone resistance in clinical isolates of Campylobacter jejuni in Sweden increased more than 20-fold at the beginning of the 1990s. Resistance to 125 microgram of ciprofloxacin per ml in clinical isolates was associated with chromosomal mutations in C. jejuni leading to a Thr-86-Ile substitution in the gyrA product and a Arg-139-Gln substitution in the parC product.
Epistemonikos ID: 3332c1fc0158d78bbd5c145ac6c202e3a9f78e01
First added on: Jan 04, 2023