Prevalence of the c.853delT Mutation of the HOXB13 Gene in Prostate Cancer in Martinique

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2021
In Martinique, prostate cancer incidence rates are nowadays among the highest worldwide with a high incidence of early-onset and familial forms. We identified a rare heterozygous germline variant c.853delT (p.Ter285Lysfs) rs77179853, reported only among patients of African ancestry with a minor allele frequency of 3.2%. We search to estimate the prevalence of this variant in a sample of prevalent prostate cancer cases managed in urology consultation in Martinique .
Epistemonikos ID: 3329dfb928dd14d1c59561806e0e33e60b104498
First added on: May 10, 2024